SEDAN · Premium gas
Mercedes-Benz E-Class (E350) Fuel Cost
Midsize executive sedan with a smooth turbo inline-four and serene highway ride. Below are estimated fuel costs based on 27 combined MPG and average US gas prices.
Best for buyers who value comfort and capability over rock-bottom fuel costs.
- Updated for 2026
- EPA-style MPG
- US avg fuel prices
- US units
- Transparent assumptions
23 MPG
32 MPG
27 MPG
17.4 gal
~470 mi
MPG breakdown
Estimated fuel cost at 12,000 miles/year
Based on 27 MPG and $4.10/gal.
Annual cost
$1822
Monthly cost
$152
Cost per mile
$0.152
Gallons / year
444
Estimate your own cost
Pre-filled with the Mercedes-Benz E-Class (E350)'s combined MPG.
Pre-filled with estimated combined MPG for the Mercedes-Benz E-Class (E350). Adjust for your real-world driving.
Estimated Annual Cost
$0.00
Per Month
$0.00
Per Mile
$0.000
~444 gallons per year
Cost by annual mileage
How much you'll spend per year at common US mileage levels (estimates).
| Miles per year | Gallons / year | Annual cost | Monthly cost |
|---|---|---|---|
| 8,000 | 296 | $1215 | $101 |
| 12,000 | 444 | $1822 | $152 |
| 15,000 | 556 | $2278 | $190 |
Estimates only. Actual costs depend on driving style, terrain, weather, and local fuel or electricity prices.
How we estimate Mercedes-Benz E-Class (E350) costs
- MPG / MPGe
- EPA-style combined city + highway figures for the base trim and recent model year.
- Fuel price
- Average US retail regular gas, premium where required, or per-kWh electricity.
- Annual mileage
- Default scenarios at 8,000 / 12,000 / 15,000 miles per year.
- Trim & year variance
- AWD, larger wheels, towing packages and older years can lower efficiency 5–15%.
Sources & assumptions
- EPA fuel economy data — City / highway / combined MPG and MPGe baselines.
- U.S. Department of Energy (fueleconomy.gov) — Vehicle efficiency and EV range references.
- AAA gas price trends — Recent national and regional retail fuel averages.
- EIA electricity rates — Average residential per-kWh prices used for EV charging.
We summarize publicly available data — no scraping, no external API calls. Figures are calibrated periodically; use the calculators above for your exact inputs.
Frequently asked questions
What is the estimated annual fuel cost for the Mercedes-Benz E-Class (E350)?
Driving 12,000 miles per year at 27 MPG and $4.10/gal, expect about $1822 per year. Heavier city driving or longer commutes will increase that.
What MPG does the Mercedes-Benz E-Class (E350) get?
Estimated EPA-style ratings are roughly 23 city / 32 highway / 27 combined MPG. Real-world numbers depend on terrain, climate and driving style.
What is the tank size of the Mercedes-Benz E-Class (E350)?
The Mercedes-Benz E-Class (E350) typically has a 17.4-gallon tank. At 27 combined MPG, that's roughly 470 miles of driving range per fill-up.
How does Mercedes-Benz E-Class (E350) fuel cost compare to other vehicles?
At 12,000 miles per year, this vehicle costs about $1822. Compare it to other sedans on our index page or use the cost-per-mile calculator to compare two specific vehicles side-by-side.
Cheaper-to-drive alternatives
Same vehicle class as the Mercedes-Benz E-Class (E350), but lower fuel or charging cost per mile. Annual cost at 12,000 mi.
Compare similar sedans
The closest competitors to the Mercedes-Benz E-Class (E350) by MPG and category.
Audi A6
sedan · premium
27 MPG
See fuel costCadillac CT4
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See fuel costToyota Avalon
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See fuel costLexus ES 350
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See fuel costBMW 5 Series (530i)
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See fuel costMercedes-Benz C-Class (C300)
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28 MPG
See fuel costCompare the Mercedes-Benz E-Class (E350) head-to-head
Side-by-side MPG, annual cost and cost-per-mile vs popular rivals.
Best road trips for the Mercedes-Benz E-Class (E350)
Popular drives that pair well with the Mercedes-Benz E-Class (E350).
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