Vehicle comparison
Mercedes-Benz E-Class (E350) vs Mercedes-Benz EQE
Side-by-side fuel and ownership cost comparison. Estimates use 12,000 mi/year at average US gas and electricity prices.
- Updated for 2026
- EPA-style MPG
- US avg fuel prices
- EV rates vary by state
- Transparent assumptions
Lowest running cost
Mercedes-Benz EQE wins on fuel cost
At 12,000 miles per year, the Mercedes-Benz EQE costs about $640 per year, roughly $1182 less than the Mercedes-Benz E-Class (E350). Over 5 years, that's about $5911 in fuel savings.
Spec & cost comparison
MPG/MPGe figures are estimates based on typical recent model years.
| Spec | Mercedes-Benz E-Class (E350) | Mercedes-Benz EQE |
|---|---|---|
| Type | SEDAN | EV |
| Fuel | Premium gas | Electric |
| City MPG/MPGe | 23 | 100 |
| Highway MPG/MPGe | 32 | 100 |
| Combined MPG/MPGe | 27 | 100 |
| Tank / Battery | 17.4 gal | 90.6 kWh |
| Energy cost | $4.10/gal | $0.16/kWh |
| Cost per mile | $0.152 | $0.053 |
Annual cost at 8k / 12k / 15k miles
Estimated yearly fuel spend at common US mileage levels.
| Miles/year | Mercedes-Benz E-Class (E350) | Mercedes-Benz EQE | Difference |
|---|---|---|---|
| 8,000 | $1215/yr · $101/mo | $427/yr · $36/mo | $788 (Mercedes-Benz EQE) |
| 12,000 | $1822/yr · $152/mo | $640/yr · $53/mo | $1182 (Mercedes-Benz EQE) |
| 15,000 | $2278/yr · $190/mo | $800/yr · $67/mo | $1478 (Mercedes-Benz EQE) |
Estimates only. Real costs depend on driving style, terrain, local gas/electricity prices and weather.
Which one is best for…
Best for commuting
Mercedes-Benz EQE
Highest combined MPG/MPGe and lowest cost per mile means cheaper daily driving.
See Mercedes-Benz EQEBest for road trips
Mercedes-Benz E-Class (E350)
Better highway efficiency, larger tank/battery and longer range between stops.
See Mercedes-Benz E-Class (E350)Best for families
Mercedes-Benz EQE
SUVs, minivans and three-row vehicles win on space and child-seat flexibility.
See Mercedes-Benz EQEBest for lowest running cost
Mercedes-Benz EQE
Cheaper energy use and lower cost per mile at every common mileage tier.
See Mercedes-Benz EQEHow we compare these vehicles
- Annual mileage
- Modeled at 12,000 mi/yr unless a scenario specifies otherwise.
- Cost per mile
- $/gal ÷ MPG, or $/kWh ÷ (MPGe ÷ 33.7) for EVs.
- EV vs gas
- Compared at average US gas and residential electricity prices — fast-charging can be 2–3× higher.
- Maintenance
- Fuel cost only — EVs typically save another $400–$1,000/yr in service and brake wear.
Sources & assumptions
- EPA fuel economy data — City / highway / combined MPG and MPGe baselines.
- U.S. Department of Energy (fueleconomy.gov) — Vehicle efficiency and EV range references.
- AAA gas price trends — Recent national and regional retail fuel averages.
- EIA electricity rates — Average residential per-kWh prices used for EV charging.
We summarize publicly available data — no scraping, no external API calls. Figures are calibrated periodically; use the calculators above for your exact inputs.
Frequently asked questions
Which is cheaper to drive, the Mercedes-Benz E-Class (E350) or Mercedes-Benz EQE?
At 12,000 miles per year, the Mercedes-Benz EQE costs about $640 per year vs $1822 for the Mercedes-Benz E-Class (E350) — roughly $1182 less per year.
What's the MPG difference between the Mercedes-Benz E-Class (E350) and Mercedes-Benz EQE?
The Mercedes-Benz E-Class (E350) is rated around 27 combined MPG versus 100 MPGe for the Mercedes-Benz EQE. Highway figures are 32 vs 100.
How much will I spend on fuel over 5 years?
Driving 12,000 miles a year for five years, expect about $9111 for the Mercedes-Benz E-Class (E350) and $3200 for the Mercedes-Benz EQE, a difference of roughly $5911.
Is the Mercedes-Benz E-Class (E350) or Mercedes-Benz EQE better for commuting?
For pure cost per mile, the Mercedes-Benz EQE wins. EVs charged at home typically deliver the lowest commuting cost, followed by hybrids and efficient compacts.
Which one is better for road trips?
Mercedes-Benz E-Class (E350) is generally the better road-trip choice — gas and hybrid vehicles win on long highway routes thanks to faster refueling, while EVs work best when charging stops fit your route.
Are these fuel cost numbers accurate for my driving?
They're estimates based on EPA-style combined MPG and average US gas and electricity prices. Real-world cost depends on local fuel prices, driving style, terrain, weather and how much city vs highway driving you do.