About the drive from San Francisco to Los Angeles
This 380-mile route between San Francisco, CA and Los Angeles, CA is one of the more popular drives in the region. Expect roughly 6 hr behind the wheel under normal traffic conditions.
Road trip tips
- I-5 north (fast) or US-101 (scenic)
- Pick your route
- Check current gas prices on AAA or GasBuddy before you leave.
- Fuel up before entering remote stretches — prices can jump 50¢/gal.
- Use cruise control on the highway to improve real-world MPG.
Fuel costs are estimates based on average gas prices and vehicle efficiency. Actual costs may vary based on traffic, weather, terrain, and driving style.