About the drive from Myrtle Beach to Orlando
This 454-mile route between Myrtle Beach, SC and Orlando, FL is a popular drive in the region. Expect roughly 7 hr 18 min behind the wheel under normal traffic conditions.
Fuel-saving tips
- Keep your speed near 65 mph — fuel economy drops sharply above 70.
- Fill up before mountain or desert stretches; remote stations charge a premium.
- Use GasBuddy or AAA to spot cheap stations along your route before you leave.