About the drive from Kansas City to Des Moines
This 212-mile route between Kansas City, MO and Des Moines, IA is a popular drive in the region. Expect roughly 3 hr 24 min behind the wheel under normal traffic conditions.
Fuel-saving tips
- Keep your speed near 65 mph — fuel economy drops sharply above 70.
- Fill up before mountain or desert stretches; remote stations charge a premium.
- Use GasBuddy or AAA to spot cheap stations along your route before you leave.