Vehicle comparison

Lexus RX 350 vs Lexus RZ 450e

Side-by-side fuel and ownership cost comparison. Estimates use 12,000 mi/year at average US gas and electricity prices.

  • Updated for 2026
  • EPA-style MPG
  • US avg fuel prices
  • EV rates vary by state
  • Transparent assumptions

Lowest running cost

Lexus RZ 450e wins on fuel cost

At 12,000 miles per year, the Lexus RZ 450e costs about $619 per year, roughly $1431 less than the Lexus RX 350. Over 5 years, that's about $7153 in fuel savings.

Spec & cost comparison

MPG/MPGe figures are estimates based on typical recent model years.

SpecLexus RX 350Lexus RZ 450e
TypeSUVEV
FuelPremium gasElectric
City MPG/MPGe21115
Highway MPG/MPGe2895
Combined MPG/MPGe24105
Tank / Battery17.2 gal71.4 kWh
Energy cost$4.10/gal$0.16/kWh
Cost per mile$0.171$0.052

Annual cost at 8k / 12k / 15k miles

Estimated yearly fuel spend at common US mileage levels.

Miles/yearLexus RX 350Lexus RZ 450eDifference
8,000$1367/yr · $114/mo$413/yr · $34/mo$954 (Lexus RZ 450e)
12,000$2050/yr · $171/mo$619/yr · $52/mo$1431 (Lexus RZ 450e)
15,000$2563/yr · $214/mo$774/yr · $65/mo$1788 (Lexus RZ 450e)

Estimates only. Real costs depend on driving style, terrain, local gas/electricity prices and weather.

Which one is best for…

How we compare these vehicles

Annual mileage
Modeled at 12,000 mi/yr unless a scenario specifies otherwise.
Cost per mile
$/gal ÷ MPG, or $/kWh ÷ (MPGe ÷ 33.7) for EVs.
EV vs gas
Compared at average US gas and residential electricity prices — fast-charging can be 2–3× higher.
Maintenance
Fuel cost only — EVs typically save another $400–$1,000/yr in service and brake wear.

Sources & assumptions

  • EPA fuel economy dataCity / highway / combined MPG and MPGe baselines.
  • U.S. Department of Energy (fueleconomy.gov)Vehicle efficiency and EV range references.
  • AAA gas price trendsRecent national and regional retail fuel averages.
  • EIA electricity ratesAverage residential per-kWh prices used for EV charging.

We summarize publicly available data — no scraping, no external API calls. Figures are calibrated periodically; use the calculators above for your exact inputs.

Frequently asked questions

Which is cheaper to drive, the Lexus RX 350 or Lexus RZ 450e?

At 12,000 miles per year, the Lexus RZ 450e costs about $619 per year vs $2050 for the Lexus RX 350 — roughly $1431 less per year.

What's the MPG difference between the Lexus RX 350 and Lexus RZ 450e?

The Lexus RX 350 is rated around 24 combined MPG versus 105 MPGe for the Lexus RZ 450e. Highway figures are 28 vs 95.

How much will I spend on fuel over 5 years?

Driving 12,000 miles a year for five years, expect about $10250 for the Lexus RX 350 and $3097 for the Lexus RZ 450e, a difference of roughly $7153.

Is the Lexus RX 350 or Lexus RZ 450e better for commuting?

For pure cost per mile, the Lexus RZ 450e wins. EVs charged at home typically deliver the lowest commuting cost, followed by hybrids and efficient compacts.

Which one is better for road trips?

Lexus RX 350 is generally the better road-trip choice — gas and hybrid vehicles win on long highway routes thanks to faster refueling, while EVs work best when charging stops fit your route.

Are these fuel cost numbers accurate for my driving?

They're estimates based on EPA-style combined MPG and average US gas and electricity prices. Real-world cost depends on local fuel prices, driving style, terrain, weather and how much city vs highway driving you do.

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